I recently wrote a paper titled: The Microbiome Theory of Aging, which was published in the peer-reviewed medical journalIntegrative Medicine, which can be accessed by clicking on the link below:
ABSTRACT: The Microbiome Theory of Aging (MTA) explains how microbial imbalance in the intestinal tract, (also called dysbiosis), causes health problems that accelerate biological aging.
The underlying mechanisms involved include increased inflammation, elevated levels of zonulin, destruction of intestinal tight junctions, and intestinal permeability, which allow lipopolysaccharides (LPS) to leak into systemic circulation. LPS is a powerful endotoxin that causes chronic inflammation throughout the body. Chronic inflammation is associated with chronic diseases and the acceleration of biological aging. Postbiotic metabolites are compounds that are created by probiotic bacteria in the colon.
Postbiotic metabolites have been called the new frontier in microbiome science due to their key roles in regulating the structure and function of the gut microbiome and many aspects of human health.
Ross Pelton, R.Ph., Ph.D., CCN
Ross Pelton is the Scientific Director for Essential Formulas, which specializes in premium probiotic products. Ross is also a clinical nutritionist, health educator, and author of 12 books. In October 1999, Ross was named one of the Top 50 Most Influential Pharmacists in America by American Druggist magazine for his work in natural medicine. Ross is also The Natural Pharmacist. His newest book is titled Rapamycin, mTOR, Autophagy & Treating mTOR Syndrome. Ross’ personal website, bio & blog are at: www.naturalpharmacist.net